Papers

Predicting resistance to small molecule kinase inhibitors

Nagarajan A, Amberg-Johnson K, Paull E, Huang K, Ghanakota P, Chandrasinghe A, Chief Elk J, Sampson JM, Wang L, Abel R, Albanese SK. Predicting Resistance to Small Molecule Kinase Inhibitors. J Chem Inf Model. 2025 Feb 20. doi: 10.1021/acs.jcim.4c02313. Epub ahead of print. PMID: 39979081.

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Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using an In Silico Enabled Drug Discovery Platform

Igawa H, Konst ZA, Therrien E, Shelley M, Koldsø H, Bos PH, Negri A, Verras A, Guo J, Dahlgren MK, Levinson A, Parr BT, Kurhade SE, Latthe P, Shetty R, Santhanakrishnan S, Amberg-Johnson K, Futran AS, Atsriku C, Pelletier RD, Liu Z, Bell JA, Bhat S, Svensson M, Gerasyuto AI. (2024). J Med Chem. 2024 Dec 26;67(24):21811-21840. doi: 10.1021/acs.jmedchem.4c01405. Epub 2024 Dec 12. PMID: 39666597.

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Ubiquitin-specific protease 7 inhibitors reveal a differentiated mechanism of p53-driven anti-cancer activity.

Futran AS, Lu T, Amberg-Johnson K, et al. (2024). iScience. 2024;27(5):109693. doi:10.1016/j.isci.2024.109693

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A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites

Tang, Y., Meister, T. R., Walczak, M., Pulkoski-Gross, M. J., Hari, S. B., Sauer, R. T., Amberg-Johnson, K., & Yeh, E. (2019) PLoS biology, 17(2).

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Host cell metabolism contributes to delayed-death kinetics of apicoplast inhibitors in Toxoplasma gondii

Amberg-Johnson, K., & Yeh, E. (2019). Antimicrob Agents Chemother. 2019 Jan 29; 63(2)

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The Toxoplasma gondii Active Serine Hydrolase 4 regulates parasite division and intravacuolar parasite architecture

Foe, IT., Onguka, O., Amberg-Johnson, K., Garner, R., Amara, N., Beatty, W., Yeh, E., Bogyo, M., mSphere. (2018).

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Chemical inhibition of apicoplast biogenesis

Amberg-Johnson, K. Ph.D. Thesis, Stanford University (2018)

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Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens

Amberg-Johnson K, Hari SB, Ganesan SM, Lorenzi HA, Sauer RT, Niles JC, Yeh E. (2017). Elife. 2017 Aug 18;6:e29865. doi: 10.7554/eLife.29865. PMID: 28826494; PMCID: PMC5576918.

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Use of Molecular Tweezers to Study the Effect of Applied Force on σ54 Core-Binding Domain

Katherine Amberg-Johnson (2012) Undergraduate Honors Thesis, UC Berkeley.

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