Katie Amberg-Johnson

An interdisciplinary and innovative scientist combining both wet-lab expertise with computational skills. A team-oriented drug discovery biologist with experience contributing in cross-functional teams. Broad interests with projects spanning oncology, liver disease, and infectious disease.

Papers

A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites

Tang, Y., Meister, T. R., Walczak, M., Pulkoski-Gross, M. J., Hari, S. B., Sauer, R. T., Amberg-Johnson, K., & Yeh, E. (2019) PLoS biology, 17(2).

Full Article

Host cell metabolism contributes to delayed-death kinetics of apicoplast inhibitors in Toxoplasma gondii

Amberg-Johnson, K., & Yeh, E. (2019). Antimicrob Agents Chemother. 2019 Jan 29; 63(2)

Full Article

The Toxoplasma gondii Active Serine Hydrolase 4 regulates parasite division and intravacuolar parasite architecture

Foe, IT., Onguka, O., Amberg-Johnson, K., Garner, R., Amara, N., Beatty, W., Yeh, E., Bogyo, M., mSphere. (2018).

Full Article

Chemical inhibition of apicoplast biogenesis

Amberg-Johnson, K. Ph.D. Thesis, Stanford University (2018)

Full Article

Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens

Katherine Amberg-Johnson, Sanjay B Hari, Suresh M Ganesan, Hernan A Lorenzi, Robert T Sauer, Jacquin C Niles, Ellen Yeh. (2017) eLife 2017;6:e29865

Full Article

Use of Molecular Tweezers to Study the Effect of Applied Force on σ54 Core-Binding Domain

Katherine Amberg-Johnson (2012) Undergraduate Honors Thesis, UC Berkeley.

Full Article

Projects

GSK Immunohack: TwoBirds 2018

I led a team in the GSK Immunohack challenge whose goal was to increase vaccinations. We won!

Hackathon Vaccinations

Vacation Contamination: Predicting Beach Water Pollution 2018

I used Gradient Boosted Decision Trees to create a predictive model for bacterial pollution based on State of Hawaii water sampling data.

Data Science

Novel antimalarial drug target identification 2016

To identify the molecular target of actinonin, we selected resistant mutants in Toxoplasma gondii that could survive high amounts of drug.

Malaria Actinonin FtsH1