GSK Immunohack: TwoBirds 2018

I led a team in the GSK Immunohack challenge whose goal was to increase vaccinations. We won!

Hackathon Vaccinations

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Vacation Contamination: Predicting Beach Water Pollution 2018

I used Gradient Boosted Decision Trees to create a predictive model for bacterial pollution based on State of Hawaii water sampling data.

Data Science

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Novel antimalarial drug target identification 2016

To identify the molecular target of actinonin, we selected resistant mutants in Toxoplasma gondii that could survive high amounts of drug.

Malaria Actinonin FtsH1

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Antimalarial drug screening and optimization 2015

A cell-based screen to identify small molecules that inhibited Plasmodium falciparum plastid organelle biogenesis.

Malaria Apicoplast Replication

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Structural Characterization of σ54 Core-Binding Domain Truncation 2012

I worked on creating a variant of the Core-Binding Domain of σ54 that lacked the C-terminal helix.

σ54 AMGEN Scholars Program

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Use of Molecular Tweezers to Study the Effect of Applied Force on σ54 Core-Binding Domain 2012

I performed a molecular tweezers experiment on the transcription initiation protein, σ54, to determine the number of unfolding events.

Molecular Tweezers σ54

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